Capsule
Pregnenolone Professional
Hormone Balance
$48.00
$1.60 a day · 30-day supply
From non-GMO wild yam, micronized in a lipid matrix for optimized absorption characteristics. May support stress management, memory, energy, sleep and a sense of well-being. Known as the mother hormone for estrogen, testosterone, progesterone, DHEA, and cortisol.
In depth
About this supplement
What Is Pregnenolone?
Pregnenolone is a steroid molecule, and the one the body makes first in the steroid pathway. It is built inside mitochondria, mostly in the adrenal glands, the gonads and the brain. This one is micronized and dispersed in a lipid base, at 100 mg per serving.
How It Works in the Body
The pathway starts from cholesterol. It is carried into the mitochondrion, where an enzyme clips off part of the side chain and leaves a 21-carbon molecule: pregnenolone. From there the route branches, one way toward progesterone, another toward DHEA.
The brain makes its own supply rather than drawing it all from the adrenal glands, which is why pregnenolone is called a neurosteroid. The pregnenolone in supplements is made in the lab from diosgenin, a sterol in wild yam; the body cannot run that conversion itself.
What It Supports
- Hormone synthesis: As the first steroid in the pathway, pregnenolone supports normal hormone synthesis.
- Stress response: The adrenal cortex makes pregnenolone alongside cortisol, so it supports a healthy stress response.
- Top of the pathway: Pregnenolone is the first steroid the body builds, and the one the others follow from.
- A neurosteroid: Brain and nerve tissue make pregnenolone locally, which is what that term means.
- Fat-soluble by nature: It is a lipid molecule, which is why this one is milled fine and carried in a lipid base.
Who It May Suit
This is a hormone precursor, so it belongs with people already working through that part of their health with a practitioner. It is not for anyone under eighteen.
Good To Know
Micronizing means the powder is milled fine and suspended in a lipid carrier, because pregnenolone does not dissolve in water. Do not use it if you are pregnant or breastfeeding. Talk with your healthcare provider before use, and be specific if you take hormone therapy or a steroid medicine, or have a hormone-sensitive condition — pregnenolone feeds that same pathway.
At a glance
Allergens and certifications
-
01
Non-GMO
FAQ
Common questions
What is pregnenolone?
A steroid molecule the body makes itself, and the first one in the steroid pathway. The adrenal glands, the gonads and the brain all make it. In supplement form it is produced in the lab from diosgenin, a plant sterol from wild yam, and this one is micronized in a lipid base.
How does the body make it?
Inside mitochondria. A transport protein carries the starting material in, and an enzyme cuts part of its side chain away, leaving the 21-carbon pregnenolone skeleton. That step is the gateway to the whole steroid pathway, which then branches toward progesterone and DHEA and onward.
What makes this form different?
It is a single-ingredient formula: pregnenolone and nothing else, at 100 mg per serving. The powder is micronized, meaning milled to a small particle size, then dispersed in a lipid matrix, because pregnenolone is fat-soluble and does not dissolve in water.
Who is it for?
Adults working with a practitioner on hormone-related questions, rather than people browsing for a general supplement. It is a single ingredient with no vitamins or botanicals alongside it. It is not for anyone pregnant or breastfeeding, and not for people under eighteen.
What should I know before taking it?
Talk with your healthcare provider before use, and be specific about everything else you take. Pregnenolone sits upstream of the body's own steroid production, so it matters if you take hormone therapy, a steroid medicine, or have a hormone-sensitive condition. Do not use it during pregnancy or breastfeeding.
Ingredients
What is in it
Every ingredient, as listed on the label.
Supplement Facts
Serving Size 1 capsule
| Ingredient | Amount Per Serving | % DV |
|---|---|---|
| Pregenolone | 100 mg | † |
† Daily Value not established.
Ingredients: Micosolle Blend, potassium hydroxde, Silicon dioxide, magnesium sulfate heptahydrate, polysorbate 80, citric acid, mircrocrystalline cellulose, vegetable oil, vegetable wax, Cab-o-sil (silica) magnesium stearate, VitaminE.
Related
Related supplements
DHEA
Hormone Balance
DHEA is a steroid hormone precursor that supports healthy androgen and estrogen levels.
$28.00
$0.93 a day
DHEA 25mg
Hormone Balance Support
Micronized dehydroepiandrosterone at 25 mg per serving. As a precursor to the androgens and estrogens, DHEA supports normal hormone synthesis.
$10.00
$0.33 a day
L-Tyrosine
Nervous System Support
Tyrosine is an amino acid that supports mood regulation, cognitive function under stress, and thyroid health.
$10.00
$0.33 a day
Lion's Mane
Cogition + Focus
Lion's mane is a culinary and traditional mushroom, here as organic material. Its beta-glucans support normal immune function.
$28.00
$0.93 a day
Selenium 200mcg
Antioxidant Support
Selenium is an essential mineral that is crucial for antioxidant defense via glutathione activity. Selenium also supports thyroid function, healthy aging, fertility, and a robust immune system.
$10.00
$0.33 a day
Sunflower Lecithin
Cognitive Function
Sunflower lecithin contains an array of nutrients that support brain health and cognitive function.
$24.00
$0.80 a day